MK2a Inhibitor, CAS 41179-33-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2'-fluoro-N-(4-hydroxyphenyl)-[1,1'-biphenyl]-4-butanamide

Purity: ≥98%

Formula Markup: C22H20FNO2

Formula Weight: 349.4

CAS Number: 41179-33-3

Notes: MK2a inhibitor is a substrate-selective inhibitor of p38α MAPK that selectively inhibits p38α-dependent phosphorylation of MAPKAPK-2 (MK2) over activating transcription factor 2 (ATF2; Ki = 330 and >20,000 nM, respectively, in cell-free assays).{46548} It inhibits proliferation of U87, A172, and U251 glioblastoma cells (EC50s = 0.6-1 μM) via inhibition of tubulin polymerization and induction of apoptosis.{46549}

• Artikelnummer: CAY17325-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 17325-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK