MM-102 (TFA), CAS 1883545-52-5

Product Description: MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki 200 times more potent than the ARA peptide.

Applications: Cancer-programmed cell death

Formula: C37H50F5N7O6

Citations: Cell Death Dis. 2022 Sep 6;13(9):770./J Mol Endocrinol. 2021 Jan;66(1):45-57./Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2961-2966. /Acta Pharmacol Sin. 2021 Apr 13.

References: [1]Karatas H, et al. High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction. J Am Chem Soc. 2013 Jan 16;135(2):669-682.

CAS Number: 1883545-52-5

Molecular Weight: 783.83

Compound Purity: 99.68

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Histone Methyltransferase

• Artikelnummer: MEXHY-12220A-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-12220A-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK