MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(rMMP3/1730), CF740 conjugate, 0.1mg/mL

MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(rMMP3/1730), CF740 conjugate, 0.1mg/mL
Artikelnummer
BTMBNC742306-500
Verpackungseinheit
500 uL
Hersteller
Biotium

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Description: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Mus musculus (mouse), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: rMMP3/1730

Immunogen: Recombinant full-length human MMP3 protein

Antibody Reactivity: MMP3

Entrez Gene ID: 4314

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)
Mehr Informationen
Artikelnummer BTMBNC742306-500
Hersteller Biotium
Hersteller Artikelnummer BNC742306-500
Verpackungseinheit 500 uL
Mengeneinheit STK
Reaktivität Human
Klonalität Recombinant
Methode Immunohistochemistry
Isotyp IgG1 kappa
Wirt Mouse
Konjugat Conjugated, CF740
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