Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 4-chloro-N-[2-(4-morpholinyl)ethyl]-benzamide-2,3,5,6-d4
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C13H13D4ClN2O2
Formula Weight: 272.7633
CAS Number: 2929883-33-8
Notes: Moclobemide-d4 is intended for use as an internal standard for the quantification of moclobemide (Item No. 24361) by GC- or LC-MS. Moclobemide is a reversible inhibitor of monoamine oxidase A (MAO-A; Ki = 0.005 µM).{23886} It is selective for MAO-A over MAO-B (Ki = 1.08 µM). Chronic administration of moclobemide (15 mg/kg) decreases immobility in the forced swim test in rats.{64015} It increases time spent in the open arms of the elevated plus maze in rats, indicating anxiolytic-like activity, when administered chronically at a dose of 20 mg/kg.{64016} Formulations containing moclobemide have been used in the treatment of major depressive disorder, bipolar disorder, and social anxiety.
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