Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein Ref Seq ID: NP_001242.2
Uniprot ID: P34810
Background: CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins.CD68 is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages [taken from NCBI Entrez Gene (Gene ID: 968)].
Immunogen: Lysosomal fraction of human lung macrophages
Clone Number: KP-1
Physical State: Liquid
Formulation: BSA-Free
Antibody Platform: COMET™,PhenoImager™ HT
Purity: Purified
Antibody Registry ID: AB_2631880