Clone Number: DCS-31
Immunogen: Purified recombinant cdk4 protein
Concentration: 0.2 mg/ml
Storage buffer: PBS with 0.2% BSA and 0.09% sodium azide
Additional info: Antibody reacts with epitope at aa 16-35. DK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a).
Applications: ICC/IF, WB, FC, IP
References: Li XR et al. Exp and Ther Medicine 2017/Kennedy AL et al. Oncotarget 2015/Clay MR et al. Am J of Surg Pathol 2016