Stock Concentration: 1000 µg/ml
Conjugate Type: Unconjugated
Buffer: Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide, BSA-Free
Shelf Life: 1 year from date of receipt
Protein Ref Seq ID: NP_061984.2
Uniprot ID: P01903
Background: In humans, Major Histocompatibility Locus (MHC) class II molecules are encoded by three different loci, HLA-DR, -DQ, and -DP, which display ∼70% similarity to each other. Polymorphism is a notable feature of MHC class II genes. HLA-DR, HLA-DP, and HLA-DQ are heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Variations in the HLA gene expression are crucial to graft survival.
Immunogen: Activated human peripheral blood mononuclear cells
Clone Number: LN3
Physical State: Liquid
Formulation: BSA-Free
Antibody Platform: COMET™,PhenoImager™ HT
Purity: Purified
Antibody Registry ID: AB_2891801
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