Target: NOS1
Conjugate: Biotin
Product Type: Monoclonal
Clone Number: J23
Immunogen: Partial Human Recombinant NOS1 Protein
Swiss-Prot: P29475
Purification: Protein A Purified
Storage Buffer: 136.36mM Ethanolamine, and 9.55mM Sodium Bicarbonate in 95.45% PBS
Concentration: 1mg/ml
Specificity: Detects ~160.97 kDa.
Cellular Localization: Cell Membrane
Tissue Specificity: Ubiquitously expressed; detected in skeletal muscle and brain, also in testis, lung and kidney.
Scientific Background: nNOS/NOS I, also known as NC-NOS, or NOS type I, or Neuronal NOS, or produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Nitric oxide production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. There are two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II).
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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