MPEP (Hydrochloride), CAS 219911-35-0

MPEP (Hydrochloride), CAS 219911-35-0
Artikelnummer
MEXHY-14609-25
Verpackungseinheit
25 mg
Hersteller
MedChemExpress

Verfügbarkeit: wird geladen...
Preis wird geladen...
Product Description: MPEP Hydrochloride is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP Hydrochloride has anxiolytic-or antidepressant-like effects[1][2]. MPEP (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Neuroscience-Neurodegeneration

Formula: C14H12ClN

References: [1]F Gasparini, et al. 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a Potent, Selective and Systemically Active mGlu5 Receptor Antagonist. Neuropharmacology. 1999 Oct;38(10):1493-503./[2]E Tatarczyńska, et al. Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist. Br J Pharmacol. 2001 Apr;132(7):1423-30.

CAS Number: 219911-35-0

Molecular Weight: 229.70

Compound Purity: 99.82

Research Area: Neurological Disease

Solubility: H2O : 25 mg/mL (ultrasonic;warming;heat to 80°C)

Target: mGluR
Mehr Informationen
Artikelnummer MEXHY-14609-25
Hersteller MedChemExpress
Hersteller Artikelnummer HY-14609-25
Verpackungseinheit 25 mg
Mengeneinheit STK
Produktinformation (PDF) Download
MSDS (PDF) Download