MRK-740, CAS 2387510-80-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-[3-(3,5-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-methyl-9-(2-methyl-4-pyridinyl)-1,4,9-triazaspiro[5.5]undecane

Purity: ≥98%

Formula Markup: C25H32N6O3

Formula Weight: 464.6

CAS Number: 2387510-80-5

Notes: MRK-740 is an inhibitor of the lysine methyltransferase PR/SET domain 9 (PRDM9; IC50 = 80 nM).{49902} It inhibits PRDM9-dependent trimethylation of ectopic histone H3K4 (IC50 = 0.8 µM) and endogenous H3K4 in HEK293 cells in a concentration-dependent manner. MRK-740 induces meiotic defects in mouse spermatocytes.

• Artikelnummer: CAY26387-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26387-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK