Product Description: MRT-81 is a potent antagonist of human and rodent smoothened (Smo) receptors, with an IC50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 can be used for the research of cancer[1].
Applications: Cancer-programmed cell death
Formula: C31H29N3O5S
References: [1]Solinas A, et al. Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity. J Med Chem. 2012 Feb 23;55(4):1559-71.
CAS Number: 1263132-08-6
Molecular Weight: 555.64
Compound Purity: 99.85
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Smo