MS 15203, CAS 73912-52-4

Description: Potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of forskolin activated adenylyl cyclase activity in rat hypothalamic memebranes). Exhibits minimal binding to a panel of ~70 GPCRs and 10 other receptors (<22% of radioligand displaced from the target receptors). Increases neuronal activity in the paraventricular nucleus. Increases food intake and body weight in mice.

CAS Number: 73912-52-4

Formula: C12H11NO5

Molecular Weight: 249,22

References: Wardman et al (2016) Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake Sci.Signal. 9 PMID:27245612

• Artikelnummer: TGMT37131-2mg
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T37131-2mg
• Verpackungseinheit: 2 mg
• Mengeneinheit: STK