Clone Name: HL4200
Light Chain: Kappa
Application Note: WB: 1:500-1:50000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody is specific for human MTHFD2 protein and does not cross react with human MTHFD2L protein.
Form: Liquid
Buffer (with preservative): PBS, no Preservative.
Concentration: batch dependent
Background: This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]
Uniprot ID: P13995
Antigen Species: Human
Immunogen: Recombinant fragment of human MTHFD2.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
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