Mulberroside A, CAS 102841-42-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 3-[(1E)-2-[4-(ß-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl, ß-D-glucopyranoside

Purity: ≥98%

Formula Markup: C26H32O14

Formula Weight: 568.52388

CAS Number: 102841-42-9

Notes: Mulberroside A is a phenol and stilbene glucoside form of oxyresveratrol (Item No. 12028) originally isolated from M. alba (mulberry) roots that has diverse biological activities.{48392,48393,48395,48394} It inhibits pregnane X receptor-mediated P-glycoprotein (P-gp) luciferase reporter activity induced by rifampicin (Item No. 14423) in LS174T cells when used at concentrations ranging from 5 to 20 μM.{48392} Mulberroside A decreases expression of TNF-α, IL-1β, and IL-6, inhibits caspase-1 activation, and increases cell viability in an isolated rat cortical neuron model of oxygen-glucose deprivation-induced ischemia and reperfusion injury.{48393} Topical administration of mulberroside A (2 and 5% v/v) reduces UVB-induced hyperpigmentation, levels of the melanogenesis enzymes tyrosinase, tyrosinase-related protein 1 (TRP-1), and microphthalmia-associated transcription factor (MITF), and tyrosinase activity in brown guinea pig skin.{48395} Mulberroside A (10, 20, and 40 mg/kg) decreases serum levels of uric acid, creatinine, and urea nitrogen, reduces renal vacuolar and granular degeneration, and increases fractional excretion of uric acid and urinary urate excretion in hyperuricemic mice.{48394}

• Artikelnummer: CAY27545-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 27545-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK