Product Description: Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC50 and MIC90 values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance[1][2].
Applications: COVID-19-immunoregulation
Formula: C73H112N22O16.C2HF3O2
References: [1]Matteo Bassetti, et al. New antibiotics for ventilator-associated pneumonia. Curr Opin Infect Dis. 2018 Jan 13./[2]Ignacio Martin-Loeches, et al. Murepavadin: a new antibiotic class in the pipeline. Expert Rev Anti Infect Ther. 2018 Apr;16(4):259-268.
Molecular Weight: 1667.83
Compound Purity: 99.83
Research Area: Infection
Solubility: H2O : 50 mg/mL (ultrasonic)
Target: Antibiotic;Bacterial