Product Description: MV1 is an antagonist of IAP (inhibitor of apoptosis protein), leads to protein knockdown of HaloTag-fused proteins when combined with HaloTag ligand[1].
Formula: C33H44N4O5
References: [1]Tomoshige S, et al. Efficient protein knockdown of HaloTag-fused proteins using hybrid molecules consisting of IAP antagonist and HaloTag ligand. Bioorg Med Chem. 2016 Jul 15;24(14):3144-8./[2]Eugene Varfolomeev, et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell. 2007 Nov 16;131(4):669-81.
CAS Number: 1001600-54-9
Molecular Weight: 576.73
Compound Purity: 98.47
Research Area: Cancer
Solubility: DMSO : ≥ 125 mg/mL
Target: Apoptosis;IAP