Product Description: N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Applications: Cancer-programmed cell death
Formula: C10H18N4O4
References: [1]Remon VAN GEEL, et al. Conjugates of antibodies an immune cell engagers. WO2021144315A1/[2]Sandeep Tharian Koshy, et al. Compositions and methods for in vivo generation of car expressing cells.WO2022040586A2