Product Description: N3-D-Orn(Boc)-OH (CHA) is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Applications: Cancer-programmed cell death
Formula: C16H31N5O4
References: [1]Remon VAN GEEL, et al. Conjugates of antibodies an immune cell engagers. WO2021144315A1/[2]Remon VAN GEEL, et al. Conjugates of antibodies an immune cell engagers. WO2021144315A1/[3]Sandeep Tharian Koshy, et al. Compositions and methods for in vivo generation of car expressing cells.WO2022040586A2
Molecular Weight: 357.45
Research Area: Others
Solubility: 10 mM in DMSO
Target: ADC Linker
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