Product Description: Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study[1][2][3].
Applications: Neuroscience-Neuromodulation
Formula: C10H18N2O6
References: [1]Pydi SP, et al. Amino acid derivatives as bitter taste receptor (T2R) blockers. J Biol Chem. 2014;289(36):25054-25066. /[2]Sidhu C, et al. Regulation of Rac1 GTPase activity by quinine through G-protein and bitter taste receptor T2R4. Mol Cell Biochem. 2017;426(1-2):129-136. /[3]Masamoto M, et al. Yoshida R. Effects of bitter receptor antagonists on behavioral lick responses of mice. Neurosci Lett. 2020;730:135041.
CAS Number: 113231-05-3
Molecular Weight: 262.26
Compound Purity: 98.80
Research Area: Others
Solubility: DMSO : 1.82 mg/mL (ultrasonic)
Target: Taste Receptor
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