NAcM-OPT, CAS 2089293-61-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-(1-butyl-4-piperidinyl)-N'-(3,4-dichlorophenyl)-N-(phenylmethyl)-urea

Purity: ≥98%

Formula Markup: C23H29Cl2N3O

Formula Weight: 434.40138

CAS Number: 2089293-61-6

Notes: An inhibitor of the UBE2M-DCNL1 protein-protein interaction (IC50 = 0.079 µM in a TR-FRET assay); selective for DCNL1 over DCNL3, DCNL4, and DCNL5 (IC50s = >50 µM) but does inhibit DCNL2 at 12.5 µM; reduces cullin 1 NEDDylation levels in CAL-33 cells at 10 µM; inhibits anchorage-independent growth in HCC95 cells at 10 µM; prevents H2O2-induced decreases in epidermal thickness, follicle length, and melanin levels in mice when intracutaneously administered at 3 mg/kg per day

• Artikelnummer: CAY42379-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42379-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK