Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (2S,3R,4S,4aR)-3,4,4a,5-tetrahydro-2,3,4,7-tetrahydroxy-[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one
Purity: ≥98%
Formula Markup: C14H13NO7
Formula Weight: 307.3
CAS Number: 29477-83-6
Notes: Narciclasine is a plant growth inhibitor that can be isolated from Narcissus bulbs. At 1 μM, it has been shown to induce apoptosis-mediated cytotoxicity in human cancer cells in vitro but not in normal fibroblasts.{32920} Narciclasine has been shown to regulate the Rho/Rho kinase/LIM kinase/cofilin signaling pathway by increasing GTPase RhoA activity, as well as inducing actin stress fiber formation in a RhoA-dependent manner.{32920}