Product Description: Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
Applications: Neuroscience-Neuromodulation
Formula: C22H37Cl3N4O
Citations: Cell Rep. 2020 Nov 10;33(6):108369. /Cell Rep. 2023 Dec 3;42(12):113551./iScience. 2023 Mar./J Headache Pain. 2022 Aug 10;23(1):98./Neurobiol Dis. 2024 Mar 8:106471./Neuroscience. 2021 Sep 9;S0306-4522(21)00454-1./Toxicol In Vitro. 2017 Oct;44:57-65.
References: [1]Koike M, et al. Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons. Neurosci Res. 1997 Sep;29(1):27-36.