(±)-NBI-74330, CAS 473722-68-8

Product Description: (±)-NBI-74330 is a potent and selective CXCR3 antagonist. (±)-NBI-74330 not only reduces tactile and thermal hypersensitivity but also enhances the analgesic properties of morphine. (±)-NBI-74330 can reduce microglial cell activation, increase astroglial cell activation, and downregulate the expression of some CXCR3 ligands in a rat neuropathic pain model[1].

Applications: COVID-19-immunoregulation

Formula: C32H27F4N5O3

References: [1]Piotrowska A, et al. Pharmacological blockade of CXCR3 by (±)-NBI-74330 reduces neuropathic pain and enhances opioid effectiveness - Evidence from in vivo and in vitro studies. Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3418-3437.

CAS Number: 473722-68-8

Molecular Weight: 605.58

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: CXCR

• Artikelnummer: MEXHY-110099-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-110099-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK