Nevirapine-d4, CAS 1051418-95-1

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 11-cyclopropyl-2,2,3,3-d4-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C15H10D4N4O

Formula Weight: 270.32226

CAS Number: 1051418-95-1

Notes: Nevirapine-d4 is intended for use as an internal standard for the quantification of nevirapine (Item No. 15117) by GC- or LC-MS. Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI).{22819} It binds to HIV-1 reverse transcriptase and inhibits RNA plus-strand initiation (IC50 = 0.45 μM). Nevirapine prevents seroconversion and viremia in a chimpanzee model of HIV-1 infection.{49140} Formulations containing nevirapine have been used in combination therapy for the treatment of HIV-1 infection.

• Artikelnummer: CAY28093-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28093-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung