Product Description: Nexturastat A is a potent, selective HDAC6 inhibitor. Nexturastat A has inhibitory for HDAC6 with an IC50 of 5 nM. Nexturastat A can be used for the research of multiple myeloma (MM)[1][2].
Applications: Cancer-programmed cell death
Formula: C19H23N3O3
References: [1]Bergman JA, et al. Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth. J Med Chem. 2012 Nov 26;55(22):9891-9./[2]Xiaoyang Sun, et al. The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma. Biosci Rep. 2019 Mar 22;39(3):BSR20181916.
CAS Number: 1403783-31-2
Molecular Weight: 341.40
Compound Purity: 98.28
Research Area: Cancer
Solubility: DMSO : ≥ 56 mg/mL
Target: HDAC