Clone Name: HL4229
Light Chain: Kappa
Application Note: WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody is specific for human RELA (NFkB p65) protein and does not cross react with human RELB (RelB) and REL (c-Rel) protein.
Form: Liquid
Buffer (with preservative): PBS, no Preservative.
Concentration: batch dependent
Background: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot ID: Q04206
Antigen Species: Human
Immunogen: Recombinant fragment of human NFkB p65.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: RELA proto-oncogene, NF-kB subunit
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