Product Description: Ningetinib Tosylate is a potent, orally bioavailable small molecule tyrosine kinase inhibitor (TKI) with IC50s of 6.7, 1.9 and c-Met, VEGFR2 and Axl, respectively.
Applications: Cancer-Kinase/protease
Formula: C38H37FN4O8S
References: [1]Ning Xi, et al. Abstract 1755: CT053PTSA, a novel c-MET and VEGFR2 inhibitor, potently suppresses angiogenesis and tumor growth. Cancer Res 2014;74(19 Suppl):Abstract nr 1755.
CAS Number: 1394820-77-9
Molecular Weight: 728.79
Compound Purity: 99.59
Research Area: Cancer
Solubility: DMSO : 33.33 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C)
Target: c-Met/HGFR;TAM Receptor;VEGFR