Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (OC-6-11)-tetrachlorobis(1H-indazole-?N2)-ruthenate(1-), monosodium salt
Purity: ≥98%
Formula Markup: C14H12Cl4N4Ru / Na
Formula Weight: 502.14261
CAS Number: 197723-00-5
Notes: NKP-1339 is a ruthenium complex with anticancer activity.{61743} It is cytotoxic to HT-29 and SW480 cells (IC50s = 24.46 and 123.3 µM, respectively). NKP-1339 induces mitochondrial apoptosis in SW480 cells. In vivo, NKP-1339 (10.5, 21, and 42 mg/kg) reduces tumor growth in a SaI/N murine fibrosarcoma model.{61744}