Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 2-amino-7-(2-furanyl)-7,9-dihydro-5(6H)-quinazolinone
Purity: ≥98%
Formula Markup: C12H11N3O2
Formula Weight: 229.2
CAS Number: 299442-43-6
Notes: NKY80 is a cell-permeable inhibitor of adenylyl cyclase (AC) that is selective for isoform AC5 over AC2 and AC3 (IC50s = 8.3 μM, 1.7 mM, and 132 μM, respectively in the presence of Gsα GTPγS-forskolin).{28956} It is a non-competitive inhibitor with respect to ATP (Item No. 14498) and forskolin (Item No. 11018) and tissue selective for AC catalytic activity in heart and lung.{28956}