Product Description: NMS-P715 is a selective, ATP-competitive inhibitor of MPS1, with an IC50 of 182 nM.
Applications: Cancer-Kinase/protease
Formula: C35H39F3N8O3
References: [1]Colombo R, et al. Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase. Cancer Res. 2010 Dec 15;70(24):10255-64./[2]Slee RB, et al. Selective inhibition of pancreatic ductal adenocarcinoma cell growth by the mitotic MPS1 kinase inhibitor NMS-P715. Mol Cancer Ther. 2014 Feb;13(2):307-315.
CAS Number: 1202055-32-0
Molecular Weight: 676.73
Compound Purity: 98.41
Research Area: Cancer
Solubility: DMSO : 2 mg/mL (ultrasonic)
Target: Mps1