Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino]-acetamide
Purity: ≥99%
Formula Markup: C13H20N2O5S
Formula Weight: 316.4
CAS Number: 161314-17-6
Notes: NNGH is a cell-permeable, broad-spectrum inhibitor of matrix metalloproteinases (MMPs). It blocks the activity of MMP-8, -9, -12, -13, and -20 with Ki values of 9, 2.6, 4.3, 3.1, and 17 nM, respectively.{27721,18673} It also inhibits MMP-1, -3, -7, and -10 with Ki values of 0.17, 0.13, 13, and 0.1 µM, respectively.{27721,18673} It is commonly used to study the role of MMP-3 (stromelysin 1) in biological systems.{27723,27724,27722}