Norcyclizine, CAS 841-77-0

Product Description: Norcyclizine is a piperazine compound that can be used for the synthesis of antimicrobial agents. 1-Benzhydrylpiperazine derivatives have been found to enhance the antibacterial activity of β-lactam antibiotics (Oxacillin, HY-B0925A) against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). This enhancement is likely achieved by inhibiting the allosteric site of PBP2a. Additionally, 1-Benzhydrylpiperazine can also serve as a pharmacological scaffold for the synthesis of anticancer agents[1][2].

Formula: C17H20N2

References: [1]Witek K, et al. Chalcogen-Varied Imidazolone Derivatives as Antibiotic Resistance Breakers in Staphylococcus aureus Strains. Antibiotics (Basel). 2023 Nov 11;12(11):1618./[2]Ananda Kumar CS et al. Synthesis and in vitro antiproliferative activity of novel 1-benzhydrylpiperazine derivatives against human cancer cell lines. Eur J Med Chem. 2009 Mar;44(3):1223-9.

CAS Number: 841-77-0

Molecular Weight: 252.35

Compound Purity: 99.73

Research Area: Cancer; Infection

Target: Antibiotic;Bacterial;Penicillin-binding protein (PBP)

• Artikelnummer: MEXHY-W013376-50G
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W013376-50G
• Verpackungseinheit: 50 g
• Mengeneinheit: STK