Nrf2 activator-10, CAS 75483-04-4

Product Description: Nrf2 activator-10 (Compound AI-1) is a PI3K-dependent inducer for antioxidant response element (ARE) (EC50 is 2.7 μM) and an activator for Nrf2. Nrf2 activator-10 modifies Keap1, blocks Cul3-Keap1 ubiquitin ligase complex, activates the transcription of Nrf2. Nrf2 activator-10 protects cells from H2O2-induced apoptosis.

Applications: Cancer-programmed cell death

Formula: C13H12ClNO3

References: [1]Hur W, et al., A small-molecule inducer of the antioxidant response element. Chem Biol. 2010 May 28;17(5):537-47.

CAS Number: 75483-04-4

Molecular Weight: 265.69

Research Area: Cancer

Target: Apoptosis;Keap1-Nrf2

• Artikelnummer: MEXHY-124834-250
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-124834-250
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK