Product Description: NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) and binds with high affinity to heteromeric α3β4 nAChR. The binding Ki values of 0.62, 25, 7.8, 55 nM for α3β4, α3β2, α4β4, α4β2, respectively[1].
Applications: Neuroscience-Neuromodulation
Formula: C12H14BrNS
References: [1]Kasper Harpsøe, et al. Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors. J Biol Chem. 2013 Jan 25;288(4):2559-70.
CAS Number: 216853-59-7
Molecular Weight: 284.22
Compound Purity: 99.78
Research Area: Neurological Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: nAChR