NSC 102533, CAS 1150-59-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-hydroxy-3-phenyl-1,4-naphthalenedione

Purity: ≥95%

Formula Markup: C16H10O3

Formula Weight: 250.3

CAS Number: 1150-59-0

Notes: A P2X7 receptor antagonist; inhibits ATP-induced dye uptake in HEK293 cells expressing human purinergic P2X7 receptors (IC50 = 22.4 nM); inhibits common lancehead (B. atrox) venom proteolysis in a concentration-dependent manner; inhibits ATP-induced IL-1ß secretion in human THP-1 monocytes and primary mouse peritoneal macrophages (IC50s = 9.8 and 11.2 nM, respectively); inhibits common lancehead (B. atrox) and jararaca (B. jararaca) venom-induced skin hemorrhage in mice when intradermally administered at 3 mg/kg; inhibits carrageenan-induced paw edema in mice at 0.01 to 1 mg/kg

• Artikelnummer: CAY42435-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42435-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK