NSC 74859, CAS 501919-59-1

Product Description: NSC 74859 (S3I-201) is a selective Stat3 inhibitor with an IC50 of 86 μM[1].

Applications: Cancer-Kinase/protease

Formula: C16H15NO7S

References: [1]Siddiquee K, et al. Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7391-6./[2]Lin L, et al. The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-β signaling. Oncogene. 2009 Feb 19;28(7):961-72./[3]Zhou C, et al. STAT3 upregulation in pituitary somatotroph adenomas induces hypersecretion. J Clin Invest. 2015 Apr;125(4):1692-702

CAS Number: 501919-59-1

Molecular Weight: 365.36

Compound Purity: 98.35

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: STAT

• Artikelnummer: MEXHY-15146-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15146-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK