Product Description: NU9056 is a potent and selective Tip60 (KAT5) histone acetyltransferase inhibitor with an [1][2] of 2 μM. NU9056 shows >16-fold selectivity for Tip60 over PCAF, p300 and GCN5. NU9056 induces apoptosis of prostate cancer cells[1].
Applications: Cancer-programmed cell death
Formula: C6H4N2S4
References: [1]Kelly Coffey, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS One. 2012;7(10):e45539./[2]Klotilda Narkaj, et al. Blocking H2A.Z Incorporation via Tip60 Inhibition Promotes Systems Consolidation of Fear Memory in Mice. eNeuro. 2018 Nov 8;5(5):ENEURO.0378-18.2018.
CAS Number: 1450644-28-6
Molecular Weight: 232.37
Compound Purity: 98.81
Research Area: Cancer
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: Apoptosis;Histone Acetyltransferase