Application Note: WB: 0.03-0.1μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 33
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89581-PEP).
Specificity/Sensitivity: This antibody is expected to recognise both report isoforms (NP_002511.1; NP_954654.1).
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
Uniprot ID: P06748
Antigen Species: Human
Immunogen: Peptide with sequence C-QEAIQDLWQWRKSL, from the C Terminus of the protein sequence according to NP_002511.1; NP_954654.1.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: nucleophosmin 1
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