Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: rel-4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone
Purity: ≥98%
Formula Markup: C30H30Cl2N4O4
Formula Weight: 581.5
CAS Number: 548472-68-0
Notes: (±)-Nutlin-3 is a racemic mixture of the p53-Mdm2 protein-protein interaction inhibitor (−)-nutlin-3 (Item No. 18585) and its less active enantiomer (+)-nutlin-3 (Item No. 10009816).{11628} In vivo, (±)-nutlin-3 (200 mg/kg twice daily) reduces tumor volume in an SJSA-1 osteosarcoma mouse xenograft model.