Product Description: Olafertinib is a third-generation EGFR TKI, with GI50 values of 5 nM (EGFR L858R/T790M), 10 nM (EGFR del19) and 689 nM (EGFR WT), respectively. Olafertinib has the potential for NSCLC research[1].
Applications: Cancer-Kinase/protease
Formula: C29H28F2N6O2
References: [1]Misako Nagasaka, et al. Beyond osimertinib: The development of 3 rd-generation EGFR Tyrosine Kinase Inhibitors. J Thorac Oncol. 2020 Dec 15;S1556-0864(20)31105-9.
CAS Number: 1660963-42-7
Molecular Weight: 530.57
Compound Purity: 99.51
Research Area: Cancer
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: EGFR