ONO-4059 (hydrochloride), CAS 1439901-97-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 6-amino-7,9-dihydro-9-[(3R)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-8H-purin-8-one, monohydrochloride

Purity: ≥98%

Formula Markup: C25H22N6O3 / HCl

Formula Weight: 490.94146

CAS Number: 1439901-97-9

Notes: ONO-4059 is an inhibitor of Bruton’s tyrosine kinase (BTK; IC50 = 2.2 nM).{30642} It is selective for BTK over LCK, LYN, and Fyn at 1 µM.{59933} ONO-4059 inhibits B cell proliferation and activation in vitro and reduces tumor growth in a TMD8 mouse xenograft model.{30642,59932}

• Artikelnummer: CAY32818-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 32818-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK