Product Description: OR-1896 is an active long-lived metabolite of Levosimendan. OR-1896 is a highly selective phosphodiesterase (PDE) III isoform inhibitor and a powerful vasodilator. OR-1896 can open ATP-sensitive K+ channels and has Ca2+-sensitizing effect. OR-1896 mitigates cardiomyocyte apoptosis, cardiac remodeling and myocardial inflammation[1].
Applications: COVID-19-immunoregulation
Formula: C13H15N3O2
References: [1]Papp, Z, et al., Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan. Int J Cardiol. 2012 Aug 23;159(2):82-7.
CAS Number: 220246-81-1
Molecular Weight: 245.282
Compound Purity: 99.03
Research Area: Cardiovascular Disease
Solubility: DMSO : 62.5 mg/mL (ultrasonic)
Target: Apoptosis;Drug Metabolite;Phosphodiesterase (PDE);Potassium Channel
Deutsch
English
