Oxythiamine (Standard), CAS 136-16-3

Oxythiamine (Standard), CAS 136-16-3
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MEXHY-107430R-0
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MedChemExpress

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Product Description: Oxythiamine (Standard) is the analytical standard of Oxythiamine. This product is intended for research and analytical applications. Oxythiamine (Hydroxythiamin), an analogue of anti-metabolite, can suppress the non-oxidative synthesis of ribose and induce cell apoptosis. Oxythiamine is a thiamine antagonist and inhibits transketolase (TK). Oxythiamine inhibits cancer cell apoptosis and inhibits cell proliferation[1][2][3].

Formula: C12H16N3O2S

References: [1]Wang J, et al. Inhibition of transketolase by oxythiamine altered dynamics of protein signals in pancreatic cancer cells. Exp Hematol Oncol. 2013 Jul 27;2:18. /[2]Raïs B, et al. Oxythiamine and dehydroepiandrosterone induce a G1 phase cycle arrest in Ehrlich's tumor cells through inhibition of the pentose cycle. FEBS Lett. 1999 Jul 30;456(1):113-8. /[3]Bai L, et al. A dose- and time-dependent effect of oxythiamine on cell growth inhibition in non-small cell lung cancer. Cogn Neurodyn. 2022 Jun;16(3):633-641. /[4]Yang CM, et al. The in vitro and in vivo anti-metastatic efficacy of oxythiamine and the possible mechanisms of action. Clin Exp Metastasis. 2010 May;27(5):341-9.

CAS Number: 136-16-3

Molecular Weight: 266.34

Research Area: Cancer

Target: Apoptosis;Endogenous Metabolite;Reference Standards
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Artikelnummer MEXHY-107430R-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-107430R-0
Verpackungseinheit Get quote
Mengeneinheit STK
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