p53-MDM2-IN-3, CAS 1542066-74-9

Product Description: p53-MDM2-IN-3 (Compound 5s) is an orally active p53-MDM2 inhibitor with a Ki value of 0.25 μM. p53-MDM2-IN-3 exerts antitumor activity by inhibiting NF-κB pathway[1].

Applications: Cancer-programmed cell death

Formula: C30H25BrFN5O

References: [1]Zhuang C, et al. Double-edged swords as cancer therapeutics: novel, orally active, small molecules simultaneously inhibit p53-MDM2 interaction and the NF-κB pathway. J Med Chem. 2014 Feb 13;57(3):567-77.

CAS Number: 1542066-74-9

Molecular Weight: 570.45

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: MDM-2/p53;NF-κB

• Artikelnummer: MEXHY-121893-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-121893-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK