Product Description: Padnarsertib (KPT-9274) is an orally bioavailable, dual PAK4/Nicotinamide phosphoribosyltransferase (Nampt) inhibitor, with IC50s of [1][2][3].
Applications: Cancer-Kinase/protease
Formula: C35H29F3N4O3
References: [1]WO2015003166A1/[2]Abu Aboud O, et al. Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth. Mol Cancer Ther. 2016 Sep;15(9):2119-29./[3]Abu Aboud O, et al. Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth.Mol Cancer Ther. 2016 Sep;15(9):2119-29.
CAS Number: 1643913-93-2
Molecular Weight: 610.63
Compound Purity: 99.86
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: NAMPT;PAK