Product Description: Paynantheine is an alkaloid with antinociceptive activity, which is found in Mitragyna speciosa. Paynantheine is also a 5-HT1AR and 5-HT2BR agonist that induces lower lip retraction and antinociception in rats[1][2].
Formula: C23H28N2O4
References: [1]Philipp AA, et al. Metabolism studies of the Kratom alkaloids mitraciliatine and isopaynantheine, diastereomers of the main alkaloids mitragynine and paynantheine, in rat and human urine using liquid chromatography-linear ion trap-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 May 1;879(15-16):1049-55./[2]León F, et al. Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors. J Med Chem. 2021 Sep 23;64(18):13510-13523.
CAS Number: 4697-66-9
Molecular Weight: 396.48
Research Area: Neurological Disease
Target: 5-HT Receptor
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