Product Description: PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Applications: Cancer-programmed cell death
Formula: C35H55N9O12S
References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
CAS Number: 1937270-46-6
Molecular Weight: 825.93
Compound Purity: 99.25
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)