Product Description: PD168393?is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC50=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC[1].
Applications: Cancer-Kinase/protease
Formula: C17H13BrN4O
References: [1]D W Fry, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.
CAS Number: 194423-15-9
Molecular Weight: 369.22
Compound Purity: 98.58
Research Area: Cancer
Solubility: DMSO : ≥ 30 mg/mL
Target: Apoptosis;Autophagy;EGFR