Clone Name: 8A89
Application Note: WB: 1:500 - 1:1000. IHC-P: 1:100 - 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 123
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
Uniprot ID: P16234
Antigen Species: Human
Immunogen: huRe-PDGF receptor
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: platelet derived growth factor receptor alpha