PDGFR TKI III, CAS 205254-94-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-phenoxyphenyl)-1-piperazinecarboxamide

Purity: ≥98%

Formula Markup: C27H27N5O4

Formula Weight: 485.5

CAS Number: 205254-94-0

Notes: A PDGFRα and PDGFRβ inhibitor (IC50s = 0.05 and 0.13 µM, respectively); selective for PDGFRα and PDGFRβ over FGFR, EGFR, PKA, and PKC (IC50s = 29.7, >30, >30, and >30 µM, respectively) but does inhibit c-Kit and FLT3 (IC50s = 0.05 and 0.23 µM, respectively); inhibits PDGF homodimer-induced proliferation of pig aorta smooth muscle cells (IC50 = 0.25 µM); inhibits the migration of primary mouse DA-MSCs induced by embryonic mouse blood at 2 µM

• Artikelnummer: CAY14925-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 14925-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK